Genetic material exchanged for engineering replacements

30% of the genetic material of an organism has been exchanged for engineering replacements, specifically 5 synthetic yeast chromosomes, as a result Synthetic Yeast Genome Project (Sc2.0).

The results of this study have been published by the journal. Science.

Synthetic chromosomes

The results are an important advance on the road towards the construction of the first fully synthetic complex organism. Specific, yeast, is a single-cell organism could produce better versions of these important products, such as new antibiotics or biofuels more environmentally friendly

The Sc2.0 project consists of a consortium of a dozen leading yeast laboratories in the United States, United Kingdom, China, France, Singapore and Australia and has set the ambitious task of producing the first synthetic yeast genome (16 chromosomes ~ 14 Mbp) for 2018.

These results are helping scientists better understand the genetic components necessary for life. Among other applications, the approach outlined with this work paves the way to a new era of gene manipulation, as in gene therapy, which currently limited to the administration of a single gene.

Video: Homologous Recombination (April 2020).