"Winter is Coming" has a real-world equivalent: Hongerwinter, that is, the Winter of Hunger, which took place between 1944 and 1945 in the Netherlands.
It was not the first or the most insidious famine in the history of mankind: heavy rains in the early 1300s reduced crops in such a way that he died a quarter of the entire European population. But the Winter of Hunger showed us to what extent hunger can change humanity, and even affect the children of the children of the children, by genetic means.
This famine was unique when it occurred in a modern, developed and literate country, suffering under the deprivations of occupation and war.
For that reason, researchers from the AMC (Academic Medical Center in Amsterdam) were able to study the so-called Hongerwinter to demonstrate how hunger affects fetal programming. Children were not only born with little weight due to their parents' hunger, but showed a greater propensity to antisocial behavior and to suffer from obesity
The actress Audrey HepburnFor example, he spent his childhood in the Netherlands during these events. During his life he suffered anemia, and respiratory diseases, and his subsequent clinical depression during adulthood has been attributed to malnutrition He suffered at an early age.